Ms. Yousafzai became the youngest winner of the Nobel Peace Prize，but people doubt whether she can _________________ create systemic(系统性的) change at this young age.

May I ask for a leave,sir? —sorry,the meeting _____ no absence.

__________for his disability made her quite unhappy.[ ]

She’s never spoken to a foreigner, — . She has been to a summer camp in the UK.

The topic___________ a heated discussion