This coat will lose its color ___________ it’s washed

Generally speaking, ______ according to the directions, the drug has no side effect [ ]

My best friend told me that he wasn’t used to ______ by plane and he used to ______ uncomfortable.

E-mail is very popular today. Peopleseldom write letters now,_______?

She was ____ sad _____ she cried when she heard the bad news.