The word "breakthrough"is often used when talking about the newest drug or the next treatment ___ in cancerresearch．

What do you think of China’s Got Talent.—________.They are so boring

Mary’s father is seriously ill, she is staying at home, looking after her ___ father.

___________she was invited to the ball made her very happy

Will you bethis afternoon, John?—I am afraid not. I have an appointment with my dentist.