It’s uncertain _______ side effect the medicine will bring about , although about two thousand patients have taken it ．

cretary worked late into the night, along speech for the president.

When someone says to you, “How beautifully you sing!” You should reply, “ .”

Could you please tell me _______—- Yes. They are playing in the park.

Michael has changed beyond recognition.—！How did he manage to lose so much weight？